Atopic dermatitis (eczema) is one of the most common and most challenging skin conditions, for patients and practitioners alike. Uniquely organized by intrinsic and extrinsic etiologies, Atopic Dermatitis: Inside Out or Outside In? examines a myriad of causes that start from both the inside of the body and from the external environment, offering physicians practical ways to design treatments that specifically address these causes. Drs. Lawrence S. Chan and Vivian Y. Shi, along with a team of expert contributing authors, examine the etiology of this complex disorder and provide targeted, comprehensive solutions and the most useful therapeutic plans based on pathophysiology, including evidence-based integrative management.

Section I: A History of Atopy 1 Historic Perspective 2 Atopy Redefined 3 Atopy of the Skin 4 Epidemiology

Section II: External Factors 5 Skin Barrier 6 Skin and Gut Microbiome 7 Immunogens 8 Nutrition 9 Oxidative Stress, Environmental factors, Pollutants 10 Clinical Evidence: External Factors

Section III: Internal  Factors 11 Keratinocytes 12 Microvasculature 13 Humoral Factors 14 Cellular Factors 15 Skin-Gut-Lung Epithelial Permeability 16 Neurosensory Mechanisms 17 Epigenetics 18 Clinical Evidence: Internal Factors

Section IV: Clinician's Corner 19 Therapeutic Guideline Overview 20 Topical Therapies 21 Wound care 22 Skin barrier Repair 23 Emerging Targeted Treatments 24 Microbiome Modulation 25 Itch and Pain Treatments 26 Complementary and Alternative Approaches 1 27 Complementary and Alternative Approaches 2

"The progress that has been made in treating atopic dermatitis has been exciting and life changing for patients. This book allows readers to stay updated and replace older references on the subject."

©Doody’s Review Service, 2022, Patricia Wong, MD (Private Practice) Doody's Score: 5 Stars!